Javed A, et al. - In the present study, researchers delineated their experience of laparoscopic bilio-enteric anastomosis [Roux-en-Y hepaticojejunostomy (LRYHJ)/laparoscopic hepaticoduodenostomy (LHD)] in the management of postcholecystectomy benign biliary strictures (BBS). In addition, they performed a comparison of the outcomes with the patients operated by the open approach. They retrospectively analyzed the prospective data of 63 patients who underwent surgery for post-cholecystectomy BBS from January 2016 to February 2019. Of these, 29 underwent laparoscopic bilio-enteric anastomosis (LRYHJ-13, LHD-16) and 34 underwent an open repair. The 2 groups were comparable concerning the median age (40 vs 39) years, type of index surgery [laparoscopic cholecystectomy (13 vs 15), laparoscopic converted to open cholecystectomy (10 vs 16), and open cholecystectomy (6 vs 3)], type of injury low stricture (7 vs 5) and high stricture (22 vs 29), preoperative biliary fistula (23 vs 30), and time from injury to repair (6 vs 7 months). However, the laparoscopy group had significantly less median intraoperative blood loss (50 mL vs 200 mL), time to resume oral diet (2 vs 4 days), and median duration of postoperative hospital stay (6 vs 8 days). The open repair group had significantly higher overall morbidity rate (within 30 days postsurgery) (38% vs 20%). These findings support the feasibility and safety of performing laparoscopic surgery for postcholecystectomy BBS with an LRYHJ or LHD and suggest that it compares favorably with the open approach.