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Lack of association between human papillomavirus types 6 and 11 genetic variants and cervical abnormalities: The Ludwig-McGill cohort study

Cancer Epidemiology, Biomarkers & Prevention Mar 20, 2019

Sichero L, et al. - Researchers examined the intra-typic genetic variability of human papillomavirus (HPV) types 6 and 11 and their influence on the development of cervical cytological abnormalities in Brazilian women. Using PCR-sequencing, they characterized variants of HPVs 6 and/or 11 in cervical swabs from women in the Ludwig-McGill Cohort Study. They estimated odds ratios (OR) and 95% confidence intervals (CI) for the associations between HPV 6 and 11 variants and cytological abnormalities using a binomial generalized estimating equations (GEE) model with logit link. As per data gained, low-risk HPVs 6 and 11 genetic variability had no association with cervical abnormalities.

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