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Keratopigmentation with micronised mineral pigments: Complications and outcomes in a series of 234 eyes

British Journal of Ophthalmology Sep 02, 2017

Alio JL, et al. – This study is performed to report the complications found in a consecutive large series of cases treated with keratopigmentation (KTP). As per their knowledge, this is the first time a study systematically and comprehensively approaches and reports KTP complications. KTP with third GP provides better results and fewer complications than previous ones. It is a modern, minimally invasive technique that helps solve several functional ocular problems and improves the cosmetic appearance of the patients. Dermatological pigments ought not to be utilized as they lead to complications; instead pigments particularly tested for the eye in terms of toxicity and teratogenicity ought to be utilized.

Methods

  • In this study, they performed KTP in 234 eyes of 204 patients for therapeutic and cosmetic reasons.
  • 50 eyes of 29 patients suffered complications from these participated patients.
  • In this study, they used different KTP techniques and three generations of pigments (GP).
  • The follow–up period ranged from 4 months to 12 years.
  • Light sensitivity (LS), visual field (VF) limitations and MRI alterations were considered functional complications.
  • Organic complications were depicted as the change in colour, colour fading and neovascularisation.

Results

  • In this study, they found the percentage of complications was 12.82%.
  • Most patients complained of LS (49%), then colour fading and change in colour (19%).
  • Neovascularisation, VF limitations and MRI complications constituted 7%, 4% and 2%, respectively.
  • Organic complications were found with the previous GP but resolved with the latest third GP with CE mark certification (Conformité Européene).
  • Although LS remained with the corneal–specific pigments, it gradually disappeared in most of the patients (81.81%) 6 months postoperatively.

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