Is there a relation between vitamin D and interleukin-17 in vitiligo? A cross-sectional study
Dermatology Oct 05, 2017
Aly D, et al. - A possible regulatory impact of vitamin D was comprehensively assessed on interleukin-17 (IL-17) along with their relation to the disease activity in vitiligo. In the pathogenesis of vitiligo, vitamin D reflected as a potential player. The regulatory association with IL-17, and its weight as a screening tool in vitiligo warranted additional exploration.
Methods
- 30 vitiligo patients and 40 controls were recruited for this trial.
- An inspection was performed of their IL-17 and vitamin D serum levels through the ELISA technique.
Results
- A prominently higher IL-17 was revealed (p = 0.001).
- In contrast, the vitamin D level appeared to be lower among the patients (p < 0.001).
- Multivariable regression gauged the link between IL-17 and vitamin D levels with the demographic data on the patients, disclosing a nonsignificant association (p > 0.05).
- A notable positive link was brought to light between vitamin D levels and the disease duration.
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