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Is mother’s own milk lactoferrin intake associated with reduced neonatal sepsis, necrotizing enterocolitis, and death?

Neonatology Feb 20, 2020

Ochoa TJ, et al. - Researchers investigated the association of maternal lactoferrin (LF: a protective protein present in milk with anti-infective and immune-modulating properties) consumption and mother’s own milk consumption in the first 10 days of life on the prevention of late-onset sepsis, necrotizing enterocolitis (NEC), or death in the first 8 weeks of life in newborns with a birth weight < 2,000 g. They conducted a retrospective cohort study enrolling 299 infants. Over days 4–10 of life, the average daily human LF intake was 283 mg/kg/day. Outcomes revealed a correlation of consumption of higher amounts of mother’s own milk in the first days of life with less infection, NEC, and death. This emphasizes strongly encouraging early human milk intake in all newborns.
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