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Is lobar size reduction a safe and value procedure compared to standard lung transplantation? A cohort study with propensity score

The Journal of Heart and Lung Transplantation Apr 09, 2020

Schiavon M, Mendogni P, Faccioli E, et al. - The waiting time to receive a standard lung transplantation may be greater than the life expectancy for patients of small dimensions or with reduced thoracic cage. For these patients, lobar reduction is suggested as an important surgical option but it is so far underutilized and lobar transplantation is suspected of high perioperative complications being technically demanding. Researchers here conducted a bicentric cohort study examining the influence of lobar lung transplantation on 1-year survival. Early and long-terms outcomes were assessed as secondary end-point. From January 2006 to December 2018, they identified 619 consecutive lung transplantation (LT) for inclusion in this retrospective study (559 standard LT, group I and 60 lobar reduction, group II). Group I and II had 1-year survival of 72% and 73%, respectively. Outcomes revealed that 1-year survival is not affected by lobar transplantation. Although the lobar transplantation group exhibited a higher rate of severe PGD at 72 hours and a slightly reduced respiratory function, no effect of these factors on the morbidity and long-term survival was observed. Positive consideration could be given to lobar transplantation to raise the donors’ pool particularly for recipients with small chest cavity.

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