Fu TS, Sklar M, Cohen M, et al. - Because frailty has emerged as a significant determinant of many health outcomes across various surgical specialties, researchers looked at the published literature on frailty reporting as a predictor of perioperative outcomes in head and neck cancer (HNC) surgery. From inception until June 2019, PubMed was searched to capture studies investigating a correlation between frailty and perioperative outcomes among HNC surgical patients. Nine series examining frailty was identified as a predictor of outcomes in HNC. Using a large population-based database like the National Surgical Quality Improvement Project or National Inpatient Sample, the majority of studies (77%) identified patients. Most studies showed a significant connection between frailty and perioperative outcomes, involving mortality, perioperative complications, and Clavien-Dindo grade IV complications. In addition, frailty was linked to greater length of hospital stay, readmission rate, and the probability of discharge to short-term or skilled nursing facilities.