Is ellipsoid zone integrity essential for visual recovery in myopic neovascularization after anti-VEGF therapy?
Graefe's Archive for Clinical and Experimental Ophthalmology Aug 18, 2017
Milani P, et al. – The objective of this study is to assess functional prognostic factors and neuroretinal changes after anti–vascular endothelial growth factor (VEGF) treatment in patients with naïve, recent myopic neovascularization (mCNV), as evaluated by spectral–domain optical coherence tomography (SD–OCT). Vision gain might occur despite ellipsoid zone or external limiting membrane (ELM) restoration. Hemorrhage could be considered a negative prognostic factor, the integrity of lesion–adjacent ELM and of the lesion–adjacent ellipsoid zone as positive prognostic factors. Myopic CNV can also resolve completely without fibrosis.
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