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Investigating the prevalence of primary thyroid dysfunction in obese and overweight individuals: Tehran thyroid study

BMC Endocrine Disorders May 05, 2021

Mahdavi M, Amouzegar A, Mehran L, et al. - In this population-based, cross-sectional study, researchers sought to examine the prevalence of thyroid dysfunctions, namely hypothyroidism and hyperthyroidism, and their correlation with BMI among adult Iranian overweight and obese people. Participants in the study were 5,353 individuals (42.5% male, 57.5% female). Anthropometric measurements were conducted. The data presented in this work showed a higher prevalence of subclinical and overt hypothyroidism among Iranian adult obese people. In addition, obesity was positively linked to increased chances of overt hypothyroidism and TPOAb positivity in obese participants even after adjustments for confounding factors. However, no link was discovered between subclinical hypothyroidism and obesity. Moreover, BMI was found to be positively related to serum TSH and TPOAb levels while negatively related to serum FT4 levels.

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