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Invasive and in situ squamous cell carcinoma of the skin: A nationwide study in Iceland

British Journal of Dermatology May 14, 2021

Adalsteinsson JA, Olafsdottir E, Ratner D, et al. - Using the Icelandic Cancer Registry, researchers assessed tumour burden of in situ and invasive cutaneous squamous cell carcinoma (cSCC) in Iceland, via this whole‐population study. A rise in in situ cSCC WSR (age‐standardized rates) from 1·2 to 19·1 for males and from 2·0 to 22·3 for females was seen between 1981 and 2017. An increase in invasive cSCC WSR was evident from 4·6 to 14 for males and from 0·3 to 13·2 for females. The average number of in situ cSCC lesions was estimated to be 1·71 per woman and 1·39 per man. In almost all anatomical locations, development of more in situ cSCCs vs invasive cSCCs was seen in women, whereas males had more invasive cSCCs, mostly on the head and neck. In Reykjavik, higher rates of in situ cSCC were observed vs rural areas. According to findings, cSCC has emerged as a growingly significant public health issue in Iceland. Possible contributors to skin cancer development are tanning bed use and travelling abroad. There is a requirement for public health efforts to stem the behaviours resulting in this swift increase in cSCC.

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