Liu K, Wang H, He W, et al. - Researchers conducted the study for testing the safety and effectiveness of intravitreal injections of conbercept vs laser photocoagulation in the treatment of diabetic macular oedema (DME). Laser photocoagulation followed by pro re nata (PRN) sham intravitreal injections (laser/sham) or sham laser photocoagulation followed by PRN 0.5 mg conbercept intravitreal injections (sham/conbercept) were given to patients with centre-involved DME. In total, 248 eyes were involved in the full analysis set and 157 eyes continued in the extension study. The use of a conbercept PRN intravitreal injection regimen improved the best-corrected visual acuity of DME patients, and its efficacy was superior to laser photocoagulations; the same efficacy was observed when the eyes treated with laser alone were switched to conbercept.