Koscal LJ, Weeda ER, Matuskowitz AJ, et al. - In this study, researchers examined how intravenous (IV) regular insulin affects glucose reduction and emergency department (ED) length of stay in patients presenting to the ED with non-emergent hyperglycemia. Further, they described the potential adverse events. In this retrospective, observational study, they included a total of 405 patients (≥ 18 years) who received IV regular insulin and were discharged from the ED at a large academic Trauma Center. Observations revealed a modest reduction in blood glucose in correlation with using > 5 units of IV regular insulin for the management of isolated hyperglycemia in the ED with no difference in ED length of stay compared with those that received ≤ 5 units. However, a 7.9% occurrence of hypokalemia was noted in correlation with using IV insulin for this purpose.