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Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: post-hoc analysis of las vegas study

BMC Anesthesiology Apr 09, 2020

Robba C, Hemmes SNT, Neto AS, et al. - Researchers designed a post-hoc analysis of the ‘Multicentre Local ASsessment of VEntilatory management during General Anaesthesia for Surgery’ (LAS VEGAS) study to explore the ventilator settings of patients undergoing neurosurgical procedures, and to analyze the correlation between perioperative variables and the development of postoperative pulmonary complications (PPCs) in neurosurgical patients. They stratified individuals into groups based on the type of surgery (brain and spine), the occurrence of PPCs and the evaluate respiratory risk in surgical patients in Catalonia score risk for PPCs. This study recruited a total of 784 patients in the analysis; 408 patients (52%) underwent spine surgery and 376 patients (48%) brain surgery.  While recruitment manoeuvres are seldom used, neurosurgical patients are ventilated with low VT and low positive end–expiratory pressure. The data displayed that intraoperative ventilator settings are not correlated with PPCs.

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