Ryan SP, Adams SB, Allen N, et al. - This study was carried out to ascertain the flammability of the skin at different time intervals after chlorhexidine-alcohol antiseptic scrub application, to provide evidence for hospital protocols recommending a 3-minute drying time. Researchers applied swine feet, which contain the skin, subcutaneous tissue, muscle, and bone, for an experimental cohort. They further conducted attempted ignition with an open flame in the presence of visible pooling, as well as at time points 0, 30, 60, and 90 seconds after application, in addition to when the skin appeared visibly dry. They applied six samples for each time point tested. According to the results, although the findings do support that a chlorhexidine-alcohol antiseptic scrub is a potentially flammable surgical prep solution, they found little support for a 3-minute time cutoff. The results of this study indicated that the presence of pooling and persistently wet appearing prep is a more important fire risk than the time elapsed after prep application. When working with any flammable solution, caution should be used, and efforts to minimize chemical burns and combustion should be sought based on evidence.