Yuenyongviwat V, et al. - A sum of 636 cases from 4 randomized controlled trials were estimated to study the consequences of an intramedullary bone plug (an instrument that surgeons use to align the distal femoral cut) with regards to postoperative blood loss in total knee arthroplasty. They observed lower rates of blood transfusion and lower level of decreased postoperative hemoglobin in candidates with the intramedullary plug as compared to subjects in whom the intramedullary canal was not plugged.