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Interventions affecting blood pressure variability and outcomes after intubating patients with spontaneous intracranial hemorrhage

The American Journal of Emergency Medicine Jul 11, 2019

Tuteja G, et al. - In view of a previous study of intubated emergency department (ED) patients indicating a reduced mortality rate in correlation to providing ≥5 interventions after initiating mechanical ventilation (pMVI), researchers examined if patients with spontaneous intracranial hemorrhage would show lower blood pressure variability (BPV) in correlation to pMVIs and thus may have improved survival rates and neurologic outcomes. In this retrospective study, they analyzed records from 147 intubated patients transferred from 40 EDs. Among these, ≥5 pMVIs were reported for 41% of patients and were associated with lower median successive variation in systolic blood pressure compared with those receiving 4 or less pMVIs. These findings suggest a significant association of individual pMVIs in addition to disease severity with BPV and patient outcomes. They recommend performing pMVIs more frequently to prevent BPV and improve patients' outcomes.
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