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Interaction between memory impairment and depressive symptoms can exacerbate anosognosia: A comparison of Alzheimer's disease with mild cognitive impairment

Aging and Mental Health May 05, 2019

Oba H, et al. - Researchers examined the impact of interactions between memory impairment, depressive symptoms, and anosognosia in 118 patients with Alzheimer's disease (AD), 47 patients with mild cognitive impairment (MCI), and 17 non-diagnosed controls. More accurate evaluation of their own memory impairment was made by patients with MCI who have no depressive symptoms vs those who have depressive symptoms and patients with AD. In patients with AD or MCI, distortion in evaluation of anosognosia for memory impairment could be observed in relation to evaluation by relatives, depressive symptoms, or activities of daily living of patients. For the correct assessment of anosognosia, patients’ medical information should include results of objective memory tests in addition to depression scale scores.

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