Shi S, Gouskova N, Najafzadeh M, et al. - Intensive blood pressure (BP) treatment may lessen death and cardiovascular events in people with type 2 diabetes who are getting standard glycemic treatment and do not have cognitive impairment.

• The study included 4,733 adults with type 2 diabetes who were at high risk of cardiovascular events.

• Over a 5-year period, the mean event-free survival time (1,825 days) was comparable between intensive and standard BP control (1,716 vs 1,714 days; mean difference, 1.3 days).

• However, intensive BP treatment was more advantageous for those assigned to standard glycemic control (1,725 vs 1,697 days; mean difference, 28.1, but not for those assigned to intensive glycemic control (1706 vs 1731 days; mean difference, −25.2 days).

• The mean event-free survival time difference between intensive and standard BP treatment was −76.0 days for those with cognitive impairment and 21.8 days for those with normal cognitive function in subgroup analysis.

• The effect was unaffected by age, gender, or baseline cardiovascular disease status.