Intensive care needs and long‐term outcome of pediatric toxic epidermal necrolysis – A 10‐year experience
International Journal of Dermatology Jul 30, 2020
Williams V, Reddy M, Bansal A, et al. - In the present study, the researchers sought to describe the clinical profile, intensive care needs, management, and outcomes (short-term and long-term) in the cohort of pediatric toxic epidermal necrolysis (TEN), defined as an acute illness with characteristic skin lesions and inflammation of two or more mucosal surfaces with skin detachment involving > 30% body surface area (%BSA), and to determine the predictors of outcomes. Between 2009 and 2018, case records of 44 children, 1 month–12 years with a diagnosis of TEN admitted to a tertiary pediatric intensive care unit have been analyzed retrospectively. The most common long‐term complication followed by skin was ocular sequelae. Immunomodulation with IVIG or steroids in comparison to conservative management alone was not associated with any mortality benefit.
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