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Intensity of perinatal care for extremely preterm babies and outcomes at a higher gestational age: Evidence from the EPIPAGE-2 cohort study

BMC Pediatrics Jan 16, 2020

Morgan AS, Khoshnood B, Diguisto C, et al. - Because perinatal decision-making affects results for extremely preterm babies (22–26 weeks’ gestational age (GA)): more effective units have enhanced survival without increased morbidity, experts sought to analyzed mortality and morbidity results at age two for babies born at 27–28 weeks’ GA in association to the intensity of perinatal care given to extremely preterm babies. They involved fetuses from the 2011 French national prospective EPIPAGE-2 cohort, alive at maternal admission to a level 3 hospital and delivered at 27–28 weeks’ GA. And examined the morbidity-free survival and overall survival at age two. A total of 633 fetuses out of 747 fetuses born at 27–28 weeks’ GA survived to age two years. Finding suggests that at two years of age no difference was observed in survival or morbidity-free survival among fetuses alive at maternal hospital admission born at 27–28 weeks’ GA, or in sensorimotor disability or presence of an ages and stages questionnaire below threshold among survivors. Moreover, at a higher gestational age, there was no proof for the impact of intensity of perinatal care for extremely preterm babies on births.
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