Cichos KH, et al. - Using the Nationwide Inpatient Sample (2005-2014), researchers performed this retrospective cohort study to investigate the prevalence of patients with neuromuscular (NM) disease undergoing total joint arthroplasty (TJA) as well as to examine its link with in-hospital complications, prolonged length of stay, and total charges. They found increased odds of total surgical complications, medical complications, and overall complications were present in NM patients undergoing TJA vs non-NM patients. Particularly, increased odds of prosthetic complications, wound dehiscence, acute postoperative anemia, altered mental status, urinary tract infection, and deep vein thrombosis were observed in NM patients. In-hospital mortality did not differ between these groups. Since more patients with NM disease become candidates of TJA, there is a need for a team of neurologists, anesthesiologists, therapists, and orthopaedic surgeon in order to anticipate, prevent, and manage potential complications.