Robijn AL, et al. - By analyzing literature data, researchers assessed the prevalence of use of inhaled corticosteroids (ICS) during pregnancy among asthmatic women, also focusing on changes of use during pregnancy vs pre-pregnancy and medication adherence among ICS users. They identified all English articles describing ICS among pregnant women with asthma from Embase, MEDLINE, CINAL and Cochrane via a systematic search. Overall 52 articles were included in this analysis. Among pregnant women with asthma, the prevalence of ICS use was estimated to be 41%, with 49% prevalence in Europe, 39% in Australia and 34% in North America. Throughout pregnancy, changes in the prescription rates for ICS were seen, with a lowered rate reported in the first trimester of pregnancy vs pre-pregnancy, and an increased rate in the second trimester and decreased in the third trimester. ICS adherence was reported in 5 studies, using 4 measures of self-reported non-adherence. Two comparable studies revealed a pooled ICS non-adherence of 40% (95%CI 36%-44%).