Zhang J, et al. - The role of lateral-wedge insoles in pain reduction and functional improvement among patients with medial knee osteoarthritis, was determined. The meta-analysis included 10 studies with a total of 938 patients, of which 478 patients received lateral-wedge insoles and 460 patients were set as control. Although the lateral-wedge insoles seemed helpful to some extent for young Asian patients within normal body mass index, no evidence demonstrating the relationship between race and role of lateral-wedge insoles on pain reduction was identified. All in all, current data do not demonstrate the efficacy of lateral-wedge insoles at attenuating knee pain and function improvement.