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Induction techniques that reduce redistribution hypothermia: A prospective, randomized, controlled, single blind effectiveness study

BMC Anesthesiology Nov 15, 2019

Roth JV, et al. - Focusing on the effect on reducing redistribution hypothermia, a comparison was performed between three different anesthetic induction techniques vs standard intravenous propofol inductions (control) in this effectiveness trial. Researchers randomly allocated elective, afebrile patients, age 18 to 55 years, to one of four groups (n = 50 each): Induction was done with 8% sevoflurane in 100% oxygen in Group “INH/100”, Group “INH/50” was induced with 8% sevoflurane in 50% oxygen and 50% nitrous oxide, Group “PROP” with 2.2 mg/kg propofol, and Group “Phnl/PROP” with 2.2 mg/kg propofol immediately preceded by 160 mcg phenylephrine. Maintenance with sevoflurane in 50% nitrous oxide and 50% oxygen in addition to opioid narcotic was offered. They used forced air warming. Post-induction, core temperatures were measured every 15 min for 1 h. Findings revealed a decrease in the magnitude of redistribution hypothermia by an average of 0.4 to 0.5 °C in patients aged 18 to 55 years as a result of inhalation inductions with sevoflurane or with prophylactic phenylephrine bolus before propofol induction.
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