Alkmark M, Keulen JKJ, Kortekaas JC, et al. - A gradual increase in the risk of perinatal death and severe neonatal morbidity has been noted after 41 weeks of pregnancy. Researchers conducted an individual participant data meta-analysis (IPD-MA) investigating if induction of labour (IOL) in uncomplicated pregnancies at 41 weeks will improve perinatal outcomes. PubMed, Excerpta Medica dataBASE (Embase), The Cochrane Library, Cumulative Index of Nursing and Allied Health Literature (CINAHL), and PsycINFO were searched for RCTs comparing IOL at 41 weeks with expectant management until 42 weeks in women with uncomplicated pregnancies. They sought individual participant data (IPD) from eligible RCTs. Three eligible RCTs (n = 5,161), and two contributed with IPD (n = 4,561) were identified from 89 full-text articles. Overall, IOL at 41 weeks was correlated with significantly decreased incidence of the composite outcome of perinatal mortality and severe neonatal morbidity, and perinatal mortality alone, without raising the risk of cesarean delivery, operative vaginal delivery, perineal lacerations III and IV, or postpartum hemorrhage. However, there remains uncertainty concerning the magnitude of the risk of perinatal mortality. A prespecified subgroup analysis suggested that in the IOL group, nulliparous but not multiparous women had a significant decrease in the risk of composite severe adverse perinatal outcome.