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Individualized positive end-expiratory pressure in obese patients during general anaesthesia: A randomized controlled clinical trial using electrical impedance tomography

British Journal of Anesthesia Nov 22, 2017

Nestler C, et al. - Researchers presumed that a combination of a recruitment manoeuvre (RM) and individualized positive end-expiratory pressure (PEEP) could abate general anaesthesia-induced atelectasis, reduced end-expiratory lung volume (EELV), and diminished arterial oxygenation in obese patients. In this study, it was demonstrated that an RM and higher individualized PEEP (PEEPIND) restored EELV, regional ventilation distribution, and oxygenation during anaesthesia in obese patients, but no persistence of these differences was seen post-extubation. Therefore, the inclusion of postoperative period in lung protection strategies was recommended.
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