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Indices of diet quality and risk of lung cancer in the Women's Health Initiative Observational Study

The Journal of Nutrition May 18, 2021

Myneni AA, Giovino GA, Millen AE, et al. - Since prospective evidence on relationships between diet quality indices and lung cancer risk is insufficient, especially among older women, researchers sought to examine connections between 4 diet quality indices [Healthy Eating Index-2015, Alternate Healthy Eating Index 2010, alternate Mediterranean Diet, and Dietary Approaches to Stop Hypertension] and lung cancer incidence and mortality in the Women's Health Initiative Observational Study. At baseline (1993–1998), postmenopausal women aged 50–79 years self-reported their diet consumption as well as details on related covariates. During ∼17 y of follow-up among 86,090 candidates, 1,491 lung cancer cases and 1,393 lung cancer deaths have been documented. After comprehensive control of smoking exposure, the authors discovered that diet quality was not linked to overall lung cancer in postmenopausal women. A high-quality diet, on the other hand, was found to be inversely related to incident squamous cell lung cancer.

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