Antwi SO, et al. - In diabetic patients who later developed hepatocellular carcinoma (HCC), researchers studied links between use of statins and metformin use pre-diagnosis and post-diagnosis on overall survival. Data from the SEER-Medicare program (2009 to 2013) were analyzed for 2,499 elderly diabetic HCC patients. In elderly diabetic HCC patients, an association was found between prediagnosis use of metformin dose ≤1500 mg/d and longer overall survival. Investigators found no association between prediagnosis metformin dose >1500 mg/d or postdiagnosis metformin use and survival, nor was there an association between use of statins either prediagnosis or post-diagnosis and survival.