Lo Vecchio A, Smarrazzo A, Amato C, et al. - Via conducting a prospective cohort study (January 1, 2009–December 31, 2018), researchers sought to determine trends in tuberculosis (TB) notification rates, correlation with migration, and changes in clinical outcomes of children living in Campania. They assessed a total of 146 children (52.1% male; median age, 50 months; interquartile range, 96.33) who received a diagnosis of TB. Analysis revealed an increase in pediatric TB rate in Campania in the last 10 years in correlation with the rise in migration. An increased likelihood of poor clinical outcomes was noted among Neelsen-positive children. Relative to Italians, foreign children displayed a lower likelihood of cure without sequelae. They accounted for all fatal cases and loss to follow-up. Emphasizing national TB rates may disregard important disparities in local infection trends and limit medical awareness concerning TB. Tailored management programs may be required for foreign children.