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Increased severity of anaemia is associated with 30-day complications following total joint replacement

The Bone & Joint Journal Apr 03, 2020

Gu A, Malahias MA, Selemon NA, et al. - In this study, the impact of the severity of anaemia on postoperative complications following total hip arthroplasty (THA) and total knee arthroplasty (TKA) was ascertained. Researchers performed a retrospective cohort study using the American College of Surgeons National Quality Improvement Program database. They distinguished and stratified all individuals who had undergone primary TKA or THA between January 2012 and December 2017 based upon hematocrit level. Applying univariate and multivariate analyses, the incidence of multiple adverse events within 30 days of arthroplasty was analyzed. The study suggests that preoperative anaemia is a risk factor for complications following primary arthroplasty. A significant association was found between the severity of anaemia and the odds of postoperative complications. It was noted that individuals who had moderate to severe anaemia were at increased risk of developing postoperative complications relative to individuals with mild anaemia. Surgeons should strongly consider correcting anaemia prior to surgery if possible, when recognizing elective primary THA or TKA in a moderately or severely anaemic patient.

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