Tabeta K, et al. - Researchers sought to investigate potential serum biomarkers of periodontitis that were related to atherosclerotic vascular disease (ASVD) and chronic periodontitis in a Japanese cross-sectional community survey. The concentrations of serum proprotein convertase subtilisin/kexin type 9 (PCSK9) and total bilirubin (TBIL) were seen to be associated with periodontal parameters in Japanese male subjects. Furthermore, for diagnosing chronic periodontitis, PCSK9 could be a candidate biomarker and it could also have potential to evaluate the risk for periodontitis to cause ASVD.