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Increased mortality from somatic multimorbidity in patients with schizophrenia: A Danish nationwide cohort study

Acta Psychiatrica Scandinavica Oct 11, 2019

Kugathasan P, et al. - In patients with schizophrenia (n = 30,210; mean age {SD} was 32.6 {11.4}) vs the general population (n = 5,402,611; mean age {SD} was 33.0 {14.5}), researchers examined the correlation of single- and multimorbidity with mortality rates. According to results, schizophrenia patients reported higher mortality at all multimorbidity levels and doubled mortality rates across all somatic diseases [ie, infections, cancer, endocrine, neurologic, cardiovascular, respiratory, digestive, skin, musculoskeletal, and urogenital diseases] vs the general population. The findings suggest that the main driver of excess mortality is the clusters and trajectories of symptoms associated with schizophrenia.
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