Buchtele N, et al. - In this prospective observational cohort study, researchers examined whether exists an optimal fibrinolysis cutoff value as determined by thrombelastometry at hospital admission to predict poor outcome in a cohort of adult patients with out-of-hospital cardiac arrest (OHCA). They analyzed patients with OHCA of presumed cardiac origin, subjected to targeted temperature management, who had achieved return of spontaneous circulation at admission to the Emergency Department of a 2,100-bed tertiary care facility in Vienna, Austria. Outcomes indicated that, in those who have experienced cardiac arrest with presumed cardiac etiology, increased fibrinolysis at admission as assessed by thrombelastometry specifically forecasts poor outcome. At admission, the maximum lysis cutoff of ≥ 20% predicted poor 30-day outcome with 100% specificity.