Huang YH, et al. - In this case-control study, researchers examined 148 individuals to determine the role of CD177 (a neutrophil surface molecule) in the pathogenesis of Kawasaki disease (KD). They observed CD177 significantly upregulated in subjects with KD vs controls with epigenetic hypomethylation. They noted a consistent CD177 expression with the Transcriptome Array 2.0 results in the PCR validation. when compared to incomplete presentation or KD with intravenous immunoglobulin (IVIG) resistance, they noted significantly higher CD177 levels in typical KD.