Incidence trends and risk factors of lung cancer in never smokers: Pooled analyses of seven cohorts
International Journal of Cancer Aug 20, 2021
Rissanen E, Heikkinen S, Seppä K, et al. - Lung cancer incidence trend is declining among never-smoker men but not in never-smoker women, likely due to tobacco control measures targeting working places and thus resulting in decreased passive smoking in men more than in women.
Data were pooled from seven Finnish health cohorts with 106,193 never smokers.
Never smoking men were 31,859 and never smoking women were 74,334.
Total 47 and 155 lung cancers were detected in these respective groups.
The average annual percent change of lung cancer incidence was −3.30% and 0.00% in never smoking men and in never smoking women, respectively.
Of five examined risk factors (education, alcohol intake, physical activity, height, and BMI), only greater height in females had a statistically significant elevated risk of lung cancer (multivariate HR = 1.84).
Possibly, exposure to passive smoking among women has continued longer in the absence of tobacco control measures targeted to domestic environments.
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