Rebman AW, et al. - Researchers performed this study in 384,652 Maryland Medicaid members enrolled from July 2004-June 2011, to analyze the incidence rate trends of first Lyme disease diagnosis in such a population. They calculated age, gender, county, season, and year-specific incidence rates. They examined the link between diagnosis and these variables by using mixed effects multiple logistic regression models. The estimated incidence rate was 97.65 per 100,000 person-years, with a 13% average annual increase in odds of diagnosis. No significant difference was observed in the incidence rates for males and females, however, males vs females were significantly more likely to be diagnosed during high season months and less likely to be diagnosed during low season months. during low season months, a diagnosis was significantly more likely to be made in adults vs children. Overall, the occurrence of Lyme disease diagnoses was reported, although relatively rare, in a Medicaid population in a Lyme-endemic state.