Incidence of allergen‐specific and total immunoglobulin E positivity in children undergoing adenotonsillectomy
Journal of Paediatrics and Child Health Mar 11, 2021
Lam ME, Kitipornchai L, Ball N, et al. - In this prospective, consecutive cohort study, researchers assessed the incidence of allergen‐specific and total immunoglobulin E (IgE) in a paediatric population undergoing adenotonsillectomy for sleep‐disordered breathing. In total, 64 consecutive patients presenting for adenotonsillectomy at a single centre were enrolled over a period of 3 months. At the time of anaesthesia induction, all patients had adenotonsillectomy and had allergen‐specific and total IgE serum testing. To determine the clinical allergy, preoperative history and examination were performed. In total, 37 (57.8%) patients had either allergen‐specific or total IgE positivity. In comparison to historical figures, the prospective, consecutive cohort of patients shows a higher rate of serum IgE positivity. Serum IgE is a useful adjunct that is linked to greater residual symptoms postadenotonsillectomy when utilised with clinical findings on history and examination.
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