Peng S, et al. - Researchers sought to determine the incidence of hepatitis B virus (HBV) intrauterine transmission in this prospective study of hepatitis B surface antigen–positive pregnant women who delivered from June 2012 to December 2016 at Wuhan Medical Care Center for Women and Children, Wuhan, China. Further, they sought the potential risk factors of HBV intrauterine transmission among these women. They noted 11 (0.9%) infants with intrauterine transmission among 1,200 women paired with 1,219 infants. Findings revealed that increasing maternal viral load can forecast intrauterine HBV transmission; the predictive rates of intrauterine transmission were 0.06%, 0.50%, 2.81%, 8.89% in infants with maternal HBV DNA levels of 10⁵, 10⁶, 10⁷, 10⁸ copies/mL, respectively. Increased risk of HBV transmission in infants was noted with vaginal delivery compared with cesarean section.