Incidence and risk factors for cannula-related venous thrombosis after venovenous extracorporeal membrane oxygenation in adult patients with acute respiratory failure
Critical Care Medicine Mar 22, 2019
Fisser C, et al. - In this retrospective, observational study, researchers examined the incidence of cannula-related thrombosis and its risk factors following venovenous extracorporeal membrane oxygenation. They found that the incidence of thrombosis was associated with risk factors like coagulation variables, cannula size, time on venovenous extracorporeal membrane oxygenation, renal failure, and underlying malignant disease. After venovenous extracorporeal membrane oxygenation, the incidence of cannula-related venous thrombosis was high. Investigators found that reduced systemic anticoagulation could enhance the risk of thrombosis. Following decannulation, sustained elevation of D-dimer might indicate thrombosis. The authors suggested that, after extracorporeal membrane oxygenation, patients should undergo routine duplex sonography to detect the formation of thrombosis in the cannulated vessel.
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