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Incidence and progression of chronic kidney disease in black and white individuals with type 2 diabetes

Clinical Journal of the American Society of Nephrology Jun 01, 2018

Gerber C, et al. - Given type 2 diabetes and associated CKD disproportionately affect blacks, researchers performed this post hoc analysis of 1937 black and 6372 white participants of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial in order to assess the associations of black race with change in eGFR and risks of developing microalbuminuria, macroalbuminuria, incident CKD (eGFR<60 ml/min per 1.73m2, ≥25% decrease from baseline eGFR, and eGFR slope <-1.6 ml/min per 1.73 m2 per year), and kidney failure or serum creatinine >3.3 mg/dl. Lower rates of incident CKD were observed in black participants enrolled in a randomized controlled trial, relative to white participants. By race, no variations were found in the rates of eGFR decline, microalbuminuria, macroalbuminuria, and kidney failure.
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