Barbieri JS, Rodriguez O, Rosenbach M, et al. - In this cross-sectional study, researchers estimated the population-based incidence and prevalence of granuloma annulare in the United States and identified the most commonly prescribed treatments. During the study period, 11,608 patients with incident granuloma annulare (8,680 female patients [74.8%]; mean [SD] age, 56.5 [18.8] years) and 17,862 patients with prevalent granuloma annulare (13,548 female patients [75.8%]; mean [SD] age, 56.6 [18.5] years) were identified. Data reported that the overall annualized incidence of granuloma annulare was 0.04% or 37.9 per 100,000, and the overall annualized prevalence of granuloma annulare was 0.06% or 58.3 per 100,000. Granuloma annulare is an uncommon disease in the United States that affects mostly women and middle-aged to older people. This cross-sectional study's findings provide important context for the basic epidemiology and overall burden of granuloma annulare in the United States.