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Incidence and predictors of recurrent and other new diabetic foot ulcers: A retrospective cohort study

Diabetic Medicine Apr 17, 2019

Engberg S, et al. - In individuals with a healed diabetic foot ulcer, researchers assessed progression rates, progression risk factors, and progression rate ratios based on whether the healed ulcer was neuropathic, neuro-ischemic, or critically ischemic. The study sample of this retrospective cohort study consisted of all individuals treated at the Steno Diabetes Centre Copenhagen foot clinic between 2010 and 2016 with a healed diabetic foot ulcer. Recurrent or other new diabetic foot ulcers were the outcome of interest. In the study period (2010–2016), 780 people had a healed diabetic foot ulcer. One-third (33.1%) developed a recurrent or other new diabetic foot ulcer per year. Investigators found that male gender, those with type 2 diabetes, and smokers had a statistically significantly higher risk of progression to a recurrent or other new diabetic foot ulcer vs those without these risk factors. Significantly higher progression rates were seen in those with neuro-ischemic or critically ischemic diabetic foot ulcers vs those with neuropathic diabetic foot ulcers. Particularly for those with ischemia, the focus should be on preventing future recurrent/other new diabetic foot ulcers.

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