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Incidence and outcomes of positive donor rim cultures and infections in the Cornea Preservation Time Study

Cornea Aug 11, 2018

Mian SI, et al. - In the Cornea Preservation Time Study (CPTS), researchers evaluated donor rim culture results and outcomes of ocular infections. As per data, cultures were performed in 784 (58.9%) of the 1330 cases. For the 0 to 7-day vs 8 to 14-day preservation time groups, respectively, the occurrence of positive fungal growth was reported in 10 of 397 (2.5%) vs 5 of 387 (1.3%) corneas, whereas positive bacterial cultures occurred in 6 of 397 (1.5%) vs 4 of 387 (1.0%) corneas. They noted that surgeon-prepared tissue was a significant risk for positive fungal cultures. A greater risk for positive bacterial cultures was observed in younger donors and accidental death donors. They concluded that, a longer preservation time was not related to a higher rate of positive donor rim cultures. A low overall rate of infection was observed across the entire cohort.
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