Reinstein DZ, et al. - The incidence, visual and refractive outcomes, optical zone enlargement, and recentration was evaluated by the researchers using topography-guided CRS-Master TOSCA II software with the MEL 80 excimer laser (Carl Zeiss Meditec AG, Jena, Germany) following primary myopic laser refractive surgery. Findings suggested that in enlarging the optical zone, recentering the optical zone, and reducing higher order aberrations, topography-guided ablation was effective. For re-treatment procedures of symptomatic patients after myopic LASIK, topography-guided custom ablation appeared to be an effective method.