Lahan S, Bharadwaj A, Cheng R, et al. - In breast cancer patients, acute myocardial infarction (AMI) was found to be linked with significantly greater odds of readmission for major bleeding within 30 days post-discharge. In such cases, management is difficult but should be based on a multidisciplinary approach and estimation of an individual patient's risk of major coronary thrombotic and bleeding events.

• Using the Nationwide Readmission Database (2016 -2018), patients admitted with AMI and underlying active colon, lung, breast, prostate, and hematological cancers were identified; of 1,524,677 index hospitalizations for AMI, 35,790 patients (2.2%) had cancer (0.9% hematological; 0.5% lung; 0.4% prostate; 0.2% breast; and 0.1% colon).

• Being about 6 to 10 years older in age, a higher proportion of atrial fibrillation, valvular heart disease, previous stroke, and a greater comorbidity burden were noted in cancer patients vs those without cancer.

• Among all types of malignancies, only active breast cancer (adjusted odds ratios 1.82) was significantly related to increased odds of readmission for major bleeding; no such link existed for recurrent AMI.