Sharma S, et al. - Investigators retrospectively examined 151 males between 2004 and 2014 to describe the predictors of recovery in semen parameters among candidates receiving clomiphene citrate (CC). They observed a significant improvement in sperm concentration (14–21 million/ml) and total motile count (TMC; 13–28 million). They also noted improvement to a TMC > 5 million among one-third of individuals who started with less than 5 million motile spermatozoon, increasing reproductive alternatives to include intrauterine insemination. They could not predict treatment response with patient characteristics, pre-treatment hormone profile and degree of oligozoospermia. They suggested clinically useful response rates to be used in shared decision-making as no predictors of improvement were recognized.