Albertsmeier M, Riedl K, Stephan AJ, et al. - Experts aspired to explore whether liver resection in a combined liver–lung-metastasised stage is justified if the pulmonary disease is not resected in this retrospective clinical cohort with a comparison group. Out of 283 patients treated for combined colorectal liver and lung metastases in the institution between 2000 and 2014, 35 patients had their pulmonary metastases left in situ while eligible for both therapy alternatives: resection vs non-resection of liver metastases. Compared with patients who did not undergo hepatic surgery, those whose liver metastases were resected exhibited significantly longer median survival. The Cox-Proportional Hazards model showed hepatic metastasectomy to be the most powerful determinant of patient survival. Findings suggested that surgical removal of liver metastases in selected patients may be beneficial even if concomitant lung metastases can not be resected.