Wang M, et al. - Researchers tested their hypothesis that the link between dialysis dose and mortality is attenuated with greater residual kidney function (RKF). In survival analyses using multivariable Cox proportional hazards regression model, they assessed the interaction between single-pool Kt/V (spKt/V) and renal urea clearance (rCL_urea) levels in 32,251 incident hemodialysis patients in a large US dialysis organization (2007–11). The expected better survival at higher hemodialysis doses was not shown by incident hemodialysis patients with substantial RKF. For incident hemodialysis patients, considering RKF levels in the decision making for the dose of dialysis treatment was recommended.