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Impact of prematurity and severe viral bronchiolitis on asthma development at 6-9 years

Journal of Asthma and Allergy Sep 23, 2020

Garcia-Garcia ML, Gonzalez-Carrasco E, Bracamonte T, et al. - Researchers aimed at comparing the burden of two conditions, severe bronchiolitis and prematurity (early and moderate-late), on asthma development at 6– 9 years. They created a retrospective cohort of all preterm (< 37weeks gestational age) and full-term children who were hospitalized for bronchiolitis, with current age between 6 and 9 years. They created a second cohort of preterm children, without admission for bronchiolitis, randomly selected from the hospital premature births database. Participants were 399 children: 133 preterm and 114 full-term cases with admission for bronchiolitis and 146 preterm control children without admission for bronchiolitis. Analysis suggests preterm birth to be an important early life risk factor for asthma in childhood. Even higher risk for subsequent asthma was observed in correlation with the addition of other risk factors, such as severe bronchiolitis, especially by rhinovirus or viral coinfections.

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