McInerney A, Tirado‐Conte G, Rodes‐Cabau J, et al. - Because there is a scarcity of data on morbidly obese (MO) patients undergoing transcatheter aortic valve replacement, researchers sought to determine their periprocedural and midterm outcomes, as well as investigate the impact of obesity phenotype. Consecutive patients with severe aortic stenosis and MO (BMI, ≥ 40 kg/m ², or ≥ 35 kg/m ² with obesity‐related comorbidities; n = 910) underwent transcatheter aortic valve replacement in 18 tertiary hospitals were compared with a nonobese cohort (BMI, 18.5–29.9 kg/m ², n = 2,264). Despite higher major vascular complications and lower device success, transcatheter aortic valve replacement in MO patients has similar short‐ and midterm outcomes to nonobese patients. An abdominal VAT:SAT ratio ≥1 indicates an obesity phenotype at increased risk of adverse clinical outcomes.